IgniREM Sleep™ · No melatonin

Fall asleep faster. Wake up without the melatonin fog.

Eight calming compounds your body already uses to wind down, enhanced to work better — for more REM sleep, fewer 3 a.m. wake-ups, and mornings that feel like mornings.

  • +24.6% more REM in a placebo-controlled study**
  • No melatonin, no antihistamines
  • 30-day money-back guarantee
See the offerfrom $129 a month

Free US shipping · Pause or cancel anytime

No melatonin
IgniREM Sleep™
IgniREM Sleep™
IgniREM Sleep™
IgniREM Sleep™

IgniREM Sleep™

Deeper, more restoring sleep from eight calming compounds — Glycine, L-Tryptophan, 5-HTP, Taurine, GABA, Vitamin C, Baicalin and Apigenin — enhanced through Igniton's process. No melatonin. No grogginess. Nothing habit-forming.

9.7k+ customer purchases
$199 retail $129 Save $70 a bottle
+25%More REM sleep**
-54%Fewer sleep interruptions**
-92%Less morning weakness**
11.5×More likely to fall back asleep fast**

1 Bottle · 60 Capsules · $4.30 per serving

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Placebo-controlled REM sleep study60 men and women aged 40–76 · +24.6% REM vs. a placebo group that declined · 54% fewer sleep interruptions · 92% less morning weakness. See the research →
Description

IgniREM Sleep is a nightly formula for deeper, more restoring sleep: eight calming amino acids and botanicals — Glycine, L-Tryptophan, 5-HTP, Taurine, GABA, Vitamin C, Baicalin and Apigenin — charged through Igniton’s proprietary process.

No melatonin, no sedatives, no antihistamines and nothing habit-forming. Take two capsules 30–60 minutes before bed. One bottle is a 30-day supply.

Featured Review

“I’ve been using Igni REM Sleep™ for about a month, and I’m so happy with it! I’m sleeping better and waking up feeling more refreshed. I especially love starting my mornings with a clearer head and steadier energy.”

— Debbi D., verified buyer

Frequently Asked Questions

Will I feel groggy in the morning?
No. There's no melatonin, antihistamine or sedative in it — the ingredients behind next-morning grogginess in most sleep products.

When will I notice a difference?
Most people report better sleep in the first night or two, and less broken sleep by the end of the first week.**

More answers in the FAQ further down the page.

Shipping

Free shipping on every US order. Subscriptions ship every 30 days, and you can pause or cancel any time. Every order is covered by our 30-day money-back guarantee.

Fall asleep — and stay asleep

GABA, Taurine and Baicalin help your nervous system shift from busy to restful, so your body can settle into sleep on its own.**

In the study, sleep interruptions fell 54% — and if you did wake at 3 AM, you were 11.5 times more likely to fall back asleep quickly.**

More of the sleep that restores you

REM is the stage in which your brain files away memories, processes emotion and recovers. Apigenin and Glycine support the depth and rhythm of the whole sleep cycle.**

In a placebo-controlled study of adults aged 40–76, IgniREM Sleep delivered 25% more REM sleep.**

Mornings that feel like mornings

No melatonin hangover, no antihistamine haze. Vitamin C supports a healthy cortisol response, so you wake up clear instead of foggy.**

In the study, morning weakness dropped 92%. Wear the sleep tracker you already own, and watch your REM line before and after.**

Why not just take melatonin?

Melatonin tells your body when to sleep. It does nothing for how deep.

Melatonin is a timing hormone. It can help you feel sleepy; it can't make the sleep you get more restorative — and the morning fog is the giveaway. IgniREM Sleep works on the system that produces REM instead.

Comparison Melatonin PM antihistamines IgniREM Sleep
What it does Signals that it's time to sleep (a timing hormone) Sedates by blocking histamine Feeds the systems that produce calm and REM sleep
Effect on REM sleep No improvement shown Suppresses REM +24.6% in a placebo-controlled study**
Morning grogginess Common at typical doses Very common — the 'hangover' None reported in the study
Tolerance over time Many report needing more Builds quickly Non-habit-forming
Hormone-free It is a hormone Hormone-free Hormone-free

+24.6% more REM in two weeks. The placebo group went backwards.

60 adults aged 40–76 wore sleep trackers for a 7-day baseline, then took either the Igniton-enhanced formula or a placebo for 14 days. The enhanced group's REM rose from about 21% to 26% of the night; the placebo group's declined.

See the studies & trade journals →

01

It's a hormone, not a nutrient

Your body makes melatonin on a schedule. Taking it every night can nudge that schedule — which is why so many people report needing more over time.

02

Sleepy isn't the same as restored

Melatonin can make you feel drowsy. It has not been shown to raise the deep, dreaming REM sleep that actually does the repair work.

03

The fog is the tell

If you wake up heavy-headed, the sleep aid is still in your system doing its job — at the wrong time. IgniREM Sleep uses nothing that lingers.

Read all 7 reasons people are throwing out their melatonin

Falls asleep faster. Stays asleep. Wakes up clear.

What customers say after their first bottle

Works like magic on the nights I take these! Tried skipping and definitely don't sleep quite as well without them.

Olga — Verified Buyer

No longer am I waking up tired, I'm actually waking up refreshed for the first time in a while.

Travis T. — Verified Buyer

I'm sleeping better and waking up feeling more refreshed. I especially love starting my mornings with a clearer head and steadier energy.

Debbi D. — Verified Buyer

It helps us sleep super well and we both wake up refreshed and ready to take on the day. Thank you!

J. Fal. — Verified Buyer

Ingredients

Eight Calming Compounds, Each Enhanced

Amino acids and botanicals your body already uses to wind down — chosen for calm, sleep depth and REM, then charged by Igniton.

Every ingredient is enhanced to work 24–39% better on average, per peer-reviewed journals

01
Glycine

The Sleep Initiator

An amino acid that supports the drop in core body temperature your body needs to enter deep sleep.

Key Benefits: Deep Sleep Onset • Temperature Regulation • Sleep Quality**

02
L-Tryptophan

The Serotonin Precursor

An essential amino acid your body turns into serotonin and melatonin — the signals that lead you into sleep.

Key Benefits: Mood Balance • Sleep Signaling • Calm Onset**

03
5-HTP

The Mood Bridge

A direct serotonin precursor that skips the slowest step of tryptophan conversion, for faster sleep-cycle support.

Key Benefits: Serotonin Production • Sleep Quality • Mood**

04
Taurine

The Nervous System Calmer

An amino acid that supports GABA activity and relaxation — the body’s first step into rest.

Key Benefits: Nervous System Calm • Stress Resilience**

05
GABA

The Quiet Switch

Your main calming neurotransmitter. Supports the shift from active to restorative.

Key Benefits: Mental Calm • Relaxation • Sleep Onset**

06
Vitamin C

The Adrenal Support

Supports a healthy cortisol response — the stress hormone that most often interrupts restorative sleep.

Key Benefits: Cortisol Balance • Adrenal Support • Recovery**

07
Baicalin

The Calm Compound

A flavonoid from Chinese skullcap that supports GABA receptor activity for deeper, longer sleep.

Key Benefits: Deep Sleep • GABA Support • Sleep Continuity**

08
Apigenin

The Sleep Architect

A bioflavonoid researched for supporting the rhythm and depth of the sleep cycle — particularly REM.

Key Benefits: REM Support • Sleep Quality • Calm**

Advisors

Guided by the people redefining human performance.

Our advisors include thought leaders in biohacking, longevity medicine, neuroscience, and advanced physics — providing scientific oversight and strategic direction.

Dave Asprey

BIOHACKING · PERFORMANCE

Dave Asprey

Father of Biohacking · 4× NYT Bestselling Author

“This is the most important new breakthrough supplement for longevity.”
Dr. Kenneth Ro, M.D.

EMERGENCY MEDICINE · MEN'S HEALTH

Dr. Kenneth Ro, M.D.

Houston-area physician and double board-certified expert in emergency and internal medicine

“I’ve seen meaningful improvements in my own focus, vitality, and recovery; and I’m confident recommending IgniCognition and IgniLongevity to patients who want to elevate their clarify, resilience and overall human potential.”
Dr. Gail King, M.D.

FUNCTIONAL MEDICINE

Dr. Gail King, M.D.

Aspen, Colorado physician specializing in women’s health, longevity, and regenerative medicine

“I am seeing profound benefits from my personal use of these products and I’m excited to recommend IgniCognition and IgniLongevity to my patients who are ready to live with more clarity, strength and coherence.”

The protocol

Part of the Igniton Protocol

IgniREM Sleep, together with IgniCognition and IgniLongevity, covers your brain and body around the clock. IgniCognition supports memory and focus through the day, IgniLongevity supports the markers that predict how you age, and IgniREM Sleep supports the deep, dreaming sleep in which the day's memories are filed away and your body recovers.

Each formula has its own job. Together they support how you think, rest and age — and every formula you add to your subscription costs less.

Complete the reset

Night and day: the NeuroReset pair

Add IgniCognition for the daytime half — sharper focus and memory — and save another $10 on every bottle, every 30 days.

Most popular pairIgniREM Sleep™IgniCognition™

NeuroReset: IgniREM Sleep + IgniCognition

Night and day. Deeper REM — when memories are filed away — plus sharper, clearer days.

$398$24838% offBoth bottles, every 30 days · free shipping
Rest + RepairIgniREM Sleep™IgniLongevity™

IgniREM Sleep + IgniLongevity

Rest and repair. Deeper sleep, plus the markers that predict how you age.

$398$24838% offBoth bottles, every 30 days · free shipping
Beauty sleepIgniREM Sleep™IgniPeptide Eye Serum™

IgniREM Sleep + IgniPeptide Eye Serum

True beauty sleep. Restoring nights, plus brighter, more rested-looking eyes.

$398$24838% offBoth bottles, every 30 days · free shipping

Questions people ask before ordering

Frequently asked questions

Does IgniREM Sleep contain melatonin?

No. There is no melatonin, no antihistamine and no sedative in the formula. It's built from eight calming compounds your body already uses — Glycine, L-Tryptophan, 5-HTP, Taurine, GABA, Vitamin C, Baicalin and Apigenin — enhanced through Igniton's process.

Will I feel groggy in the morning?

No. Morning grogginess comes from sleep aids that are still active when you wake — melatonin at higher doses, and PM antihistamines in particular. IgniREM Sleep uses nothing that lingers. In the placebo-controlled study, participants reported 92% less morning weakness.**

How quickly does it work?

Most people notice they fall asleep more easily within the first few nights, and sleep with fewer interruptions by the end of the first week. In the study, REM sleep was 24.6% higher after 14 days.** Give it a full bottle — 30 nights — to judge it properly; if it isn't for you, the 30-day guarantee covers you.

Does it help with sleep debt — catching up after short nights?

Sleep debt is mostly a shortage of deep and REM sleep, not just hours in bed. IgniREM Sleep is designed to raise the share of the night spent in REM, which is the part that restores memory and mood — so the sleep you do get does more.

Will it stop working or make me dependent?

No. It's non-habit-forming and supports your own sleep mechanisms rather than overriding them, so there is no tolerance to build and nothing to taper off.

Can I take it with other supplements or medications?

It pairs well with most routines. Because 5-HTP and L-Tryptophan support serotonin, check with your doctor first if you take sleep medication, an SSRI or anything else that affects serotonin, or if you are pregnant or nursing.

How do I take it?

Two capsules with water 30–60 minutes before bed. One bottle is 60 capsules — a 30-night supply.

What does the subscription include, and can I cancel?

Subscribe & Save ships a fresh bottle every 30 days with free US shipping at $129 a month, and you can pause, skip or cancel any time from your account — no calls, no minimum term. Every order is covered by the 30-day money-back guarantee.

Try IgniREM Sleep risk-free

DISCLAIMER: The information on this page — including articles, videos, testimonials and other materials — is provided for informational and educational purposes only.

Our formulas are backed by university research published in peer-reviewed journals. Study results describe group averages; individual results vary.

Nothing here is medical advice or is intended to diagnose, treat, cure or prevent any disease. The personal stories shared are unique to each person and are not a guarantee of results. Always consult a healthcare professional before starting any new supplement. These statements have not been evaluated by the Food and Drug Administration.